Martindale Category: Skeletal Muscle Relaxant
Generic Name: Methocarbamol
Strength: Relaxivar® 1g/10ml (Methocarbamol)
Classification: Skeletal Muscle Relaxant
Therapeutic Use: 1.Muscle Spasm: Adjunctive treatment of muscle spasm associated with acute painful musculoskeletal conditions.
2. Tetanus: Adjunct therapy for tetanus.

Relaxivar is a muscle relaxing medication used short term with physical therapy and other treatments to control uncomfortable and painful symptoms caused by muscle strains and sprains.

IM, Slow IV Injection (max. 3 ml/minute), IV Infusion

Adult
Muscle Spasm:
IM, IV: Initial: 1 g; may repeat every 8 hours; maximum dose: 3 g/day for no more than 3 consecutive days. If condition persists, may repeat course of therapy after a drug-free interval of 48 hours.
Tetanus:
Adjunct therapy: Initial 1-2 g IV injection (at 300 mg/min), then additional 1-2 g IV infusion for a total dose of 3 g initially. May repeat 1-2 g IV every 6 hours until can give NG or PO. Total of 24 g PO may be needed.
Pediatric
Postoperative Pain, Adjunct:
Children ≥4 years and Adolescents:
Postoperative day (POD) 0: IV: 10 mg/kg/dose every 6 to 8 hours for 48 to 72 hours. Maximum adult daily dose: 3,000 mg/day for no more than 3 consecutive days.
POD 2 or 3: Oral: 10 mg/kg/dose every 6 to 8 hours. Maximum adult daily dose: 4,000 mg/day.
Tetanus:
Infants, Children, and Adolescents:
IV: 15 mg/kg/dose or 500 mg/m2/dose; may repeat every 6 hours as needed; usual adult dose: 1,000 to 2,000 mg/dose; maximum total dose: 1.8 g/m2 for 3 days; in adults, injection is not recommended for use longer than 3 days.

CNS effects and fall/injury risk

Drowsiness

Dizziness

Leukopenia (IV)

Lightheadedness

Blurred vision

Headache

Fever

Nausea

Anorexia

Adynamic ileus

Dysgeusia

GI upset

Nystagmus

Diplopia

Flushing

Vertigo

Mild muscular incoordination

Syncope

Hypotension

Bradycardia

Urticaria

Pruritus

Rash

Skin eruptions

Conjunctivitis with nasal congestion

Anaphylactic reactions

Thrombophlebitis (IV)

Sloughing (IV)

Injection site pain (IV)

Hemolysis (IV)

Increased Hgb and RBCs in urine (IV)

Seizures (IV)

Azelastine (Nasal): Avoid combination.
Bromperidol: Avoid combination.
Flunarizine: Avoid combination.
Kratom: Avoid combination.
Nabilone: Avoid combination.
Noscapine: Avoid combination.
Olopatadine (Nasal): Avoid combination.
Orphenadrine: Avoid combination.
Oxomemazine: Avoid combination.
Paraldehyde: Avoid combination.
Thalidomide: Avoid combination.

Store below 30°C.
Protect from light and freezing.br> Keep out of the sight and reach of children.